江南-欧盟评估转基因米曲霉菌株 NZYM

欧盟评估转基因米曲霉菌株 NZYM-FL出产的三酰甘油脂肪酶的平安性时候：2024-12-20 10:25来历：食物火伴网作者： 泽夕 焦点提醒：2024年12月18日，欧盟食物平安局就一种食物酶三酰甘油脂肪酶（triacylglycerol lipase）的平安性评价发布定见。 食物火伴网讯 2024年12月18日，欧盟食物平安局就一种食物酶三酰甘油脂肪酶（triacylglycerol lipase）的平安性评价发布定见。 据领会，这类食物酶是由转基因米曲霉菌株 NZYM-FL出产的，旨在用在两种食物出产进程。 颠末评估，专家小组得出结论，该食物酶在预期的利用前提下不会引发平安问题。部门原文报导以下： The food enzyme triacylglycerol lipase (triacylglycerol acylhydrolase, EC 3.1.1.3) is produced with the genetically modified Aspergillus oryzae strain NZYM-FL by Novozymes A/S. A safety evaluation of this food enzyme was made previously, in which EFSA concluded that, under the intended conditions of use, this food enzyme did not give rise to safety concerns. Due to the implementation of a new methodology to estimate the dietary exposure to food enzymes in 2016, the European Commission requested EFSA to revise the exposure assessment of this food enzyme by using this new methodology. In this assessment, EFSA realigned the intended uses of this food enzyme to two food manufacturing processes and recalculated the dietary exposure. As the food enzyme-total organic solids (TOS) are removed in one food manufacturing process, the dietary exposure to the food enzyme-TOS was estimated only for the remaining process. It was calculated to be up to 0.492 mg TOS/kg body weight (bw) per day in European populations. When combined with the no observed adverse effect level previously reported (340 mg TOS/kg bw per day, the mid-dose tested), the Panel derived a margin of exposure of at least 691. based on the revised exposure estimate, the margin of exposure calculated thereof and the previous evaluation, the Panel concluded that this food enzyme does not give rise to safety concerns under the intended conditions of use. 本文由食物火伴网食物资讯中间编纂，供网友参考，有任何疑问，请联系news@foodmate.net。